node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
G3UL45_LOXAF | HDHD3 | ENSLAFP00000028554 | ENSLAFP00000023134 | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | Haloacid dehalogenase like hydrolase domain containing 3. | 0.582 |
G3UL45_LOXAF | MTAP | ENSLAFP00000028554 | ENSLAFP00000008012 | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.694 |
G3UL45_LOXAF | NUDT12 | ENSLAFP00000028554 | ENSLAFP00000021318 | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | Nudix hydrolase 12. | 0.814 |
G3UL45_LOXAF | PNP | ENSLAFP00000028554 | ENSLAFP00000003122 | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.700 |
GNE | HDHD3 | ENSLAFP00000014809 | ENSLAFP00000023134 | Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. | Haloacid dehalogenase like hydrolase domain containing 3. | 0.570 |
HDHD3 | G3UL45_LOXAF | ENSLAFP00000023134 | ENSLAFP00000028554 | Haloacid dehalogenase like hydrolase domain containing 3. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.582 |
HDHD3 | GNE | ENSLAFP00000023134 | ENSLAFP00000014809 | Haloacid dehalogenase like hydrolase domain containing 3. | Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. | 0.570 |
HDHD3 | MTAP | ENSLAFP00000023134 | ENSLAFP00000008012 | Haloacid dehalogenase like hydrolase domain containing 3. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.632 |
HDHD3 | NDRG3 | ENSLAFP00000023134 | ENSLAFP00000022273 | Haloacid dehalogenase like hydrolase domain containing 3. | NDRG family member 3. | 0.550 |
HDHD3 | NT5E | ENSLAFP00000023134 | ENSLAFP00000000205 | Haloacid dehalogenase like hydrolase domain containing 3. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.582 |
HDHD3 | NUDT12 | ENSLAFP00000023134 | ENSLAFP00000021318 | Haloacid dehalogenase like hydrolase domain containing 3. | Nudix hydrolase 12. | 0.543 |
HDHD3 | PNP | ENSLAFP00000023134 | ENSLAFP00000003122 | Haloacid dehalogenase like hydrolase domain containing 3. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.642 |
HDHD3 | PSAT1 | ENSLAFP00000023134 | ENSLAFP00000015019 | Haloacid dehalogenase like hydrolase domain containing 3. | Phosphoserine aminotransferase. | 0.744 |
HDHD3 | SHMT1 | ENSLAFP00000023134 | ENSLAFP00000007740 | Haloacid dehalogenase like hydrolase domain containing 3. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.553 |
HDHD3 | SHMT2 | ENSLAFP00000023134 | ENSLAFP00000009635 | Haloacid dehalogenase like hydrolase domain containing 3. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.553 |
MTAP | G3UL45_LOXAF | ENSLAFP00000008012 | ENSLAFP00000028554 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.694 |
MTAP | HDHD3 | ENSLAFP00000008012 | ENSLAFP00000023134 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Haloacid dehalogenase like hydrolase domain containing 3. | 0.632 |
MTAP | NT5E | ENSLAFP00000008012 | ENSLAFP00000000205 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.694 |
MTAP | PNP | ENSLAFP00000008012 | ENSLAFP00000003122 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.603 |
NDRG3 | HDHD3 | ENSLAFP00000022273 | ENSLAFP00000023134 | NDRG family member 3. | Haloacid dehalogenase like hydrolase domain containing 3. | 0.550 |