STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENAHENAH actin regulator. (789 aa)    
Predicted Functional Partners:
EVL
Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.
    
0.926
VASP
Vasodilator stimulated phosphoprotein.
    
0.926
TES
Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity); Belongs to the prickle / espinas / testin family.
   
 0.880
NEK2
NIMA related kinase 2.
    
 0.601
NF1
Neurofibromin 1.
    
 0.601
ESRP2
Epithelial splicing regulatory protein 2.
      
 0.559
ESRP1
Epithelial splicing regulatory protein 1.
      
 0.555
LPP
LIM domain containing preferred translocation partner in lipoma.
   
 0.539
TRIP6
Thyroid hormone receptor interactor 6.
   
 0.539
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 
 0.531
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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