STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (481 aa)    
Predicted Functional Partners:
METAP1
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
    
 0.949
DEGS1
Delta 4-desaturase, sphingolipid 1.
 
    
 0.895
DEGS2
Delta 4-desaturase, sphingolipid 2.
 
    
 0.895
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.885
RPL23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.885
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
  
 
 0.859
RPL11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 
 0.829
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.812
G3TRE8_LOXAF
Ubiquitin-like domain-containing protein.
   
 
 0.812
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
   
  
 0.810
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.