STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)    
Predicted Functional Partners:
NOTCH1
Uncharacterized protein.
    
 0.958
NOTCH2
Notch receptor 2.
    
 0.934
WWP1
E3 ubiquitin-protein ligase.
    
 0.642
ITCH
E3 ubiquitin-protein ligase.
    
 0.642
WWP2
E3 ubiquitin-protein ligase.
    
 0.642
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.469
G3U9C8_LOXAF
Ubiquitin-like domain-containing protein.
    
  0.469
SMURF2
E3 ubiquitin-protein ligase.
    
 0.456
HECW1
E3 ubiquitin-protein ligase.
    
 0.456
NEDD4L
E3 ubiquitin-protein ligase.
    
 0.456
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.