STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC37Cell division cycle 37. (381 aa)    
Predicted Functional Partners:
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
    
 
 0.969
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 0.876
HSP90B1
Heat shock protein 90 beta family member 1.
    
 0.864
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.856
STIP1
Stress induced phosphoprotein 1.
   
 0.854
PPP5C
Serine/threonine-protein phosphatase.
    
 0.850
TSC1
TSC complex subunit 1.
    
 0.825
HSP90AA1
HATPase_c domain-containing protein.
   
 0.814
G3ULS6_LOXAF
Uncharacterized protein.
   
 0.814
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.777
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.