STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK8Mitogen-activated protein kinase. (428 aa)    
Predicted Functional Partners:
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
  
0.993
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
 0.993
MAPK9
Mitogen-activated protein kinase.
  
 
0.990
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
0.981
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
    
 0.975
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
   
 0.973
NFATC3
Nuclear factor of activated T cells 3.
    
 0.965
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.959
FOSL2
FOS like 2, AP-1 transcription factor subunit.
    
 0.957
RAC2
Rac family small GTPase 2.
   
 0.952
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.