STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.974
CBL
Cbl proto-oncogene.
    
 0.893
CBLC
Cbl proto-oncogene C.
    
 0.875
EGFR
Receptor protein-tyrosine kinase.
    
 0.810
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
  
 
 
0.785
SYNJ1
Synaptojanin 1.
    
 
 0.758
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
  
 
 
0.747
SYNJ2
Synaptojanin 2.
    
 
 0.723
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 0.709
IGF1R
Tyrosine-protein kinase receptor.
    
 0.701
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.