STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCLS1Hematopoietic cell-specific Lyn substrate 1. (487 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
 0.823
WASL
WASP like actin nucleation promoting factor.
   
 0.783
HDAC6
Histone deacetylase 6.
    
 0.762
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 
 0.750
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
    
 0.747
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.738
GSN
Gelsolin.
   
 0.724
SCIN
Scinderin.
    
 0.723
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
 0.695
SH3PXD2A
SH3 and PX domains 2A.
    
 0.683
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.