STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP2Insulin like growth factor binding protein 2. (178 aa)    
Predicted Functional Partners:
G3TG57_LOXAF
IlGF domain-containing protein.
   
 0.914
IGF2
Insulin like growth factor 2.
   
 0.904
GHSR
Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.525
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.523
GDF9
Growth differentiation factor 9.
      
 0.496
IGFBP7
Insulin like growth factor binding protein 7.
      
 0.491
IGF1R
Tyrosine-protein kinase receptor.
   
 
 0.456
PTPRB
Protein tyrosine phosphatase receptor type B.
    
 
 0.439
IGF2R
Insulin like growth factor 2 receptor.
      
 0.415
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.