STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GREM2Gremlin 2, DAN family BMP antagonist. (170 aa)    
Predicted Functional Partners:
GDF5
Growth differentiation factor 5.
    
 0.969
GDF6
Growth differentiation factor 6.
    
 0.956
BMP4
Bone morphogenetic protein 4.
    
 0.940
BMP2
Bone morphogenetic protein 2.
    
 0.940
BMP7
Bone morphogenetic protein 7.
    
 0.914
BMP5
Bone morphogenetic protein 5.
    
 0.914
BMP6
Bone morphogenetic protein 6.
    
 0.911
BMP8A
TGF_BETA_2 domain-containing protein.
    
  0.902
GREM1
Gremlin.
  
  
 
0.902
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.