STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPTNOptineurin. (588 aa)    
Predicted Functional Partners:
TBK1
TANK binding kinase 1.
    
 0.960
GABARAP
GABA type A receptor-associated protein.
    
 0.913
GABARAPL1
GABA type A receptor associated protein like 1.
    
 0.913
TANK
TRAF family member associated NFKB activator.
     
 0.904
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.850
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.850
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.682
CALCOCO2
Calcium binding and coiled-coil domain 2.
    
 0.609
RAB8B
RAB8B, member RAS oncogene family.
     
 0.573
RAB8A
RAB8A, member RAS oncogene family.
     
 0.573
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.