STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN1Calpain 1; Belongs to the peptidase C2 family. (703 aa)    
Predicted Functional Partners:
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
  0.908
CASP12
Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family.
   
 0.908
CDK5R1
Cyclin-dependent kinase 5 activator.
   
 
 0.906
BAK1
BCL2 antagonist/killer 1.
   
 0.904
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
  
  
0.904
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.903
CAST
Calpastatin.
   
 0.813
CAPNS1
Calpain small subunit 1.
   
0.673
CAPNS2
Calpain small subunit 2.
   
0.673
SKP2
S-phase kinase associated protein 2.
      
 0.547
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.