STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1350 aa)    
Predicted Functional Partners:
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
 0.982
MAPK9
Mitogen-activated protein kinase.
   
 0.974
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
 0.966
MAPK10
Mitogen-activated protein kinase.
   
 0.944
MAPK8
Mitogen-activated protein kinase.
   
 0.944
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
 0.922
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
    
 0.902
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.893
KLC1
Uncharacterized protein.
    
 
 0.888
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
   
 
 0.837
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.