STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIFKNucleolar protein interacting with the FHA domain of MKI67. (318 aa)    
Predicted Functional Partners:
RSL1D1
Ribosomal L1 domain containing 1.
   
 
 0.999
BRIX1
Biogenesis of ribosomes BRX1.
   
 
 0.998
DDX18
RNA helicase.
   
 
 0.997
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.997
NIP7
60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.
   
 
 0.996
RPF1
Ribosome production factor 1 homolog.
   
 
 0.996
RPF2
Ribosome production factor 2 homolog.
   
 
 0.996
NOC2L
Uncharacterized protein.
   
 
 0.996
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.995
RSL24D1
Ribosomal L24 domain containing 1.
   
 
 0.993
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.