STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SF3A3Splicing factor 3a subunit 3. (502 aa)    
Predicted Functional Partners:
SF3A2
Splicing factor 3a subunit 2.
    
 0.998
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
 0.998
SF3B2
Splicing factor 3b subunit 2.
   
 0.997
SF3B4
Splicing factor 3b subunit 4.
    
 0.997
SF3B3
Splicing factor 3b subunit 3.
   
 0.997
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
   
 0.995
DDX46
DEAD-box helicase 46.
   
 0.994
SF3B5
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
   
 0.994
SF3B1
Splicing factor 3b subunit 1.
   
 0.992
PRPF6
Pre-mRNA processing factor 6.
   
 0.992
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.