STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKS2Poly [ADP-ribose] polymerase. (1247 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
    
 0.898
SH3BP2
SH3 domain binding protein 2.
    
 
 0.888
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 
 0.877
RNF146
Ring finger protein 146.
    
 0.873
TERF1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
    
 0.871
AXIN2
Axin 2.
    
 0.853
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.698
G3TVG9_LOXAF
Uncharacterized protein.
    
 
 0.698
TNKS1BP1
Tankyrase 1 binding protein 1.
    
 
 0.673
GMDS
GDP-mannose 4,6-dehydratase.
    
 
 0.584
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.