STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK2Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (638 aa)    
Predicted Functional Partners:
SCG5
Secretogranin V.
   
 
 0.861
BSND
Barttin CLCNK type accessory beta subunit.
      
 0.697
CPE
Carboxypeptidase E.
   
  
 0.695
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.659
PTPRN
Protein tyrosine phosphatase receptor type N.
   
 
 0.580
PTPRN2
Uncharacterized protein.
   
 
 0.580
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.560
ZBTB24
Zinc finger and BTB domain containing 24.
    
 0.489
POFUT1
Protein O-fucosyltransferase 1.
   
  
 0.480
AK7
Adenylate kinase 7.
   
  
 0.477
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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