STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT8Keratin 8; Belongs to the intermediate filament family. (493 aa)    
Predicted Functional Partners:
KRT18
Keratin 18; Belongs to the intermediate filament family.
   
0.994
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.874
KRT19
Keratin 19; Belongs to the intermediate filament family.
   
0.638
BAG3
BCL2 associated athanogene 3.
    
 0.636
KRT7
Keratin 7; Belongs to the intermediate filament family.
  
0.559
PKP3
Plakophilin 3.
   
 
 0.547
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
   
 
 0.543
PKP1
Plakophilin 1.
   
 
 0.524
EGFR
Receptor protein-tyrosine kinase.
    
 0.524
NBR1
NBR1 autophagy cargo receptor.
    
 0.520
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.