Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-3NK2 homeobox 3. (370 aa)    
Predicted Functional Partners:
HAND2
Heart and neural crest derivatives expressed 2.
    
 0.596
PTPN21
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
   
  
 0.573
CEBPB
CCAAT/enhancer-binding protein.
    
 
 0.564
RALGAPA1
Ral GTPase activating protein catalytic alpha subunit 1.
      
 0.529
PRR7
Proline rich 7, synaptic.
      
 0.527
POLR3C
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.526
HIVEP3
Human immunodeficiency virus type I enhancer binding protein 3.
   
  
 0.515
SLC25A44
Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.513
MADCAM1
Adhes-Ig_like domain-containing protein.
   
 
 0.508
TRIM24
Tripartite motif containing 24.
      
 0.507
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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