STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)    
Predicted Functional Partners:
LAMP5
Lysosomal associated membrane protein family member 5.
   
  
 0.727
GABRG1
Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.686
KCNAB1
Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.
   
 0.646
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
    
 0.642
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.597
CACNA2D1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
  
 0.574
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha.
    
 
 0.565
CAMK2D
Calcium/calmodulin dependent protein kinase II delta.
    
 
 0.565
CAMK2B
Calcium/calmodulin dependent protein kinase II beta.
    
 
 0.565
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 
 0.564
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.