STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (827 aa)    
Predicted Functional Partners:
PSME2
Proteasome activator subunit 2.
   
  
 0.834
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
      
 0.810
ZNF76
Zinc finger protein 76.
   
  
 0.766
SRPRB
SRP receptor subunit beta.
    
 
 0.658
LYNX1
UPAR/Ly6 domain-containing protein.
      
 0.640
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
   
 
 0.627
MYSM1
Myb like, SWIRM and MPN domains 1.
   
  
 0.578
UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C- terminal glycine of ubiquitin (By similarity). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity); Belongs to the peptidase C12 family.
      
 0.562
CDC26
Cell division cycle 26.
   
  
 0.548
RAD50
RAD50 double strand break repair protein.
   
  
 0.510
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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