STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (262 aa)    
Predicted Functional Partners:
SPINK6
Serine peptidase inhibitor, Kazal type 6.
    
 0.813
ZFAND4
Zinc finger AN1-type containing 4.
    
 0.708
SPINK5
Serine peptidase inhibitor, Kazal type 5.
   
 0.621
LOC100146723
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.594
F6Y785_HORSE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.594
TGM5
Transglutaminase 5.
    
 0.586
F6WB66_HORSE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.558
RXFP4
Relaxin family peptide/INSL5 receptor 4.
   
 0.537
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.526
ENAM
Enamelin.
      
 0.495
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.