Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LARP1BLa ribonucleoprotein domain family member 1B. (1106 aa)    
Predicted Functional Partners:
LARP1
La ribonucleoprotein domain family member 1.
   
   0.921
ZCCHC13
Zinc finger CCHC-type containing 13.
   
 
 0.859
RRP12
Ribosomal RNA processing 12 homolog.
   
  
 0.821
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 
 0.702
TRIM69
Tripartite motif containing 69.
   
 
 0.697
DKC1
Dyskerin pseudouridine synthase 1.
   
 
 0.649
DHX15
DEAH-box helicase 15.
   
 
 0.644
EIF3G
Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]
   
 
 0.580
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
 
 0.556
EDRF1
Erythroid differentiation regulatory factor 1.
      
 0.545
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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