MSRA protein (Equus caballus) - STRING interaction network

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Predicted Interactions

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Score

MSRA

Methionine sulfoxide reductase A. (266 aa)

Predicted Functional Partners:

TXN

0.929

TXNDC8

0.850

NME8

0.832

TXN2

0.827

GNMT

0.824

TXNDC2

0.817

MSRB3

0.813

LOC111772259

0.812

MSRB2-2

0.811

MSRB2

0.810

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNMT	LOC111772259	ENSECAP00000015434	ENSECAP00000025243	Glycine N-methyltransferase.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.634
GNMT	MSRA	ENSECAP00000015434	ENSECAP00000001142	Glycine N-methyltransferase.	Methionine sulfoxide reductase A.	0.824
GNMT	MSRB2	ENSECAP00000015434	ENSECAP00000028978	Glycine N-methyltransferase.	MsrB domain-containing protein.	0.634
GNMT	MSRB2-2	ENSECAP00000015434	ENSECAP00000040461	Glycine N-methyltransferase.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.634
LOC111772259	GNMT	ENSECAP00000025243	ENSECAP00000015434	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Glycine N-methyltransferase.	0.634
LOC111772259	MSRA	ENSECAP00000025243	ENSECAP00000001142	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Methionine sulfoxide reductase A.	0.812
LOC111772259	NME8	ENSECAP00000025243	ENSECAP00000039114	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	NME/NM23 family member 8.	0.441
LOC111772259	TXN	ENSECAP00000025243	ENSECAP00000011207	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...]	0.590
LOC111772259	TXNDC2	ENSECAP00000025243	ENSECAP00000006479	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Thioredoxin domain containing 2.	0.448
LOC111772259	TXNDC8	ENSECAP00000025243	ENSECAP00000019003	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Thioredoxin domain containing 8.	0.444
MSRA	GNMT	ENSECAP00000001142	ENSECAP00000015434	Methionine sulfoxide reductase A.	Glycine N-methyltransferase.	0.824
MSRA	LOC111772259	ENSECAP00000001142	ENSECAP00000025243	Methionine sulfoxide reductase A.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.812
MSRA	MSRB2	ENSECAP00000001142	ENSECAP00000028978	Methionine sulfoxide reductase A.	MsrB domain-containing protein.	0.810
MSRA	MSRB2-2	ENSECAP00000001142	ENSECAP00000040461	Methionine sulfoxide reductase A.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.811
MSRA	MSRB3	ENSECAP00000001142	ENSECAP00000033206	Methionine sulfoxide reductase A.	Methionine sulfoxide reductase B3.	0.813
MSRA	NME8	ENSECAP00000001142	ENSECAP00000039114	Methionine sulfoxide reductase A.	NME/NM23 family member 8.	0.832
MSRA	TXN	ENSECAP00000001142	ENSECAP00000011207	Methionine sulfoxide reductase A.	Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...]	0.929
MSRA	TXN2	ENSECAP00000001142	ENSECAP00000028442	Methionine sulfoxide reductase A.	Thioredoxin 2.	0.827
MSRA	TXNDC2	ENSECAP00000001142	ENSECAP00000006479	Methionine sulfoxide reductase A.	Thioredoxin domain containing 2.	0.817
MSRA	TXNDC8	ENSECAP00000001142	ENSECAP00000019003	Methionine sulfoxide reductase A.	Thioredoxin domain containing 8.	0.850