STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)    
Predicted Functional Partners:
ABCC8
ATP binding cassette subfamily C member 8.
 
 
 0.999
ABCC9-2
Uncharacterized protein.
 
 
 0.946
LOC111772371
Uncharacterized protein.
 
 
 0.946
ENSECAP00000048584
Uncharacterized protein.
 
 
 0.946
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
   
 0.931
RAPGEF3
Rap guanine nucleotide exchange factor 3.
   
 
 0.863
TPH1
Secretion regulating guanine nucleotide exchange factor.
     
 0.746
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 
 0.736
CACNA1A
Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.
   
 
 0.640
SLC2A2
Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.636
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.