KCNJ11 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KCNJ11

Potassium voltage-gated channel subfamily J member 11. (390 aa)

Predicted Functional Partners:

ABCC8

0.999

ABCC9-2

0.920

GABBR1

0.893

LOC111772371

0.892

ENSECAP00000048584

0.892

GABBR2

0.891

RAPGEF3

0.874

RAPGEF4

0.845

KCNA7

0.786

TPH1

0.766

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	ABCC9-2	ENSECAP00000018853	ENSECAP00000045232	ATP binding cassette subfamily C member 8.	Uncharacterized protein.	0.523
ABCC8	ENSECAP00000048584	ENSECAP00000018853	ENSECAP00000048584	ATP binding cassette subfamily C member 8.	Uncharacterized protein.	0.523
ABCC8	KCNJ11	ENSECAP00000018853	ENSECAP00000001166	ATP binding cassette subfamily C member 8.	Potassium voltage-gated channel subfamily J member 11.	0.999
ABCC8	LOC111772371	ENSECAP00000018853	ENSECAP00000046323	ATP binding cassette subfamily C member 8.	Uncharacterized protein.	0.523
ABCC8	RAPGEF3	ENSECAP00000018853	ENSECAP00000005437	ATP binding cassette subfamily C member 8.	Rap guanine nucleotide exchange factor 3.	0.889
ABCC8	RAPGEF4	ENSECAP00000018853	ENSECAP00000043922	ATP binding cassette subfamily C member 8.	Rap guanine nucleotide exchange factor 4.	0.969
ABCC8	TPH1	ENSECAP00000018853	ENSECAP00000036252	ATP binding cassette subfamily C member 8.	Secretion regulating guanine nucleotide exchange factor.	0.714
ABCC9-2	ABCC8	ENSECAP00000045232	ENSECAP00000018853	Uncharacterized protein.	ATP binding cassette subfamily C member 8.	0.523
ABCC9-2	KCNJ11	ENSECAP00000045232	ENSECAP00000001166	Uncharacterized protein.	Potassium voltage-gated channel subfamily J member 11.	0.920
ABCC9-2	RAPGEF3	ENSECAP00000045232	ENSECAP00000005437	Uncharacterized protein.	Rap guanine nucleotide exchange factor 3.	0.560
ABCC9-2	RAPGEF4	ENSECAP00000045232	ENSECAP00000043922	Uncharacterized protein.	Rap guanine nucleotide exchange factor 4.	0.736
ENSECAP00000048584	ABCC8	ENSECAP00000048584	ENSECAP00000018853	Uncharacterized protein.	ATP binding cassette subfamily C member 8.	0.523
ENSECAP00000048584	KCNJ11	ENSECAP00000048584	ENSECAP00000001166	Uncharacterized protein.	Potassium voltage-gated channel subfamily J member 11.	0.892
ENSECAP00000048584	LOC111772371	ENSECAP00000048584	ENSECAP00000046323	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSECAP00000048584	RAPGEF3	ENSECAP00000048584	ENSECAP00000005437	Uncharacterized protein.	Rap guanine nucleotide exchange factor 3.	0.560
ENSECAP00000048584	RAPGEF4	ENSECAP00000048584	ENSECAP00000043922	Uncharacterized protein.	Rap guanine nucleotide exchange factor 4.	0.736
GABBR1	GABBR2	ENSECAP00000049330	ENSECAP00000007287	Gamma-aminobutyric acid type B receptor subunit 1.	Gamma-aminobutyric acid type B receptor subunit 2.	0.999
GABBR1	KCNJ11	ENSECAP00000049330	ENSECAP00000001166	Gamma-aminobutyric acid type B receptor subunit 1.	Potassium voltage-gated channel subfamily J member 11.	0.893
GABBR2	GABBR1	ENSECAP00000007287	ENSECAP00000049330	Gamma-aminobutyric acid type B receptor subunit 2.	Gamma-aminobutyric acid type B receptor subunit 1.	0.999
GABBR2	KCNJ11	ENSECAP00000007287	ENSECAP00000001166	Gamma-aminobutyric acid type B receptor subunit 2.	Potassium voltage-gated channel subfamily J member 11.	0.891