Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PANX3Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (392 aa)    
Predicted Functional Partners:
TRUB2
TruB pseudouridine synthase family member 2.
      
 0.604
GP1BB
Glycoprotein Ib platelet subunit beta.
      
 0.572
TMEM38B
Transmembrane protein 38B.
      
 0.515
OSTN
Osteocrin.
      
 0.510
ENTPD1
Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.
      
 0.459
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
      
 0.459
ANKH
ANKH inorganic pyrophosphate transport regulator.
      
 0.456
C1QTNF3
C1q domain-containing protein.
      
 0.448
IBSP
Integrin binding sialoprotein.
   
  
 0.427
GJA10
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.403
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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