Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
S1PR4Sphingosine-1-phosphate receptor 4. (542 aa)    
Predicted Functional Partners:
S1PR5
Sphingosine-1-phosphate receptor 5.
     
0.831
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
0.829
GNA12
G protein subunit alpha 12.
    
 0.828
GNA13
G protein subunit alpha 13.
    
 0.801
S1PR1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.799
SPHK2
Sphingosine kinase 2.
      
 0.763
SPHK1
Sphingosine kinase 1.
      
 0.671
GPR84
G protein-coupled receptor 84.
   
 
 0.629
GNA15
G protein subunit alpha 15.
    
 0.626
SGPL1
Sphingosine-1-phosphate lyase 1.
      
 0.576
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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