Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHLDA1PH domain-containing protein. (372 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
    
 0.933
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
    
  0.595
AURKC
Aurora kinase C; Belongs to the protein kinase superfamily.
    
  0.595
KCTD11
Potassium channel tetramerization domain containing 11.
      
 0.590
SLC35B4
Solute carrier family 35 member B4.
      
 0.529
PHF21A
PHD finger protein 21A.
      
 0.529
ANKRD34C
Ankyrin repeat domain 34C.
      
 0.526
PPARA
Peroxisome proliferator activated receptor alpha.
     
  0.510
SRRT
Serrate, RNA effector molecule.
      
 0.460
SYT8
Synaptotagmin 8.
      
 0.459
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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