Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADHFE1Alcohol dehydrogenase iron containing 1. (507 aa)    
Predicted Functional Partners:
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.869
SORD
Sorbitol dehydrogenase.
  
 
 0.809
DNAJC5B
DnaJ heat shock protein family (Hsp40) member C5 beta.
   
  
 0.802
CMBL
Carboxymethylenebutenolidase homolog.
  
 
 0.785
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8.
   
 
 0.761
AGXT
Serine--pyruvate aminotransferase.
    
 0.758
ALDH6A1
Aldehyde dehydrogenase 6 family member A1.
   
 
 0.733
LOC100057768
Beta_elim_lyase domain-containing protein.
    
 0.731
HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.717
PUDP
Pseudouridine 5'-phosphatase.
    
 0.715
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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