Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEURL2Neuralized E3 ubiquitin protein ligase 2. (285 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
     
 0.845
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.830
SPATA25
Spermatogenesis associated 25.
      
 0.787
ASB5
Ankyrin repeat and SOCS box containing 5.
    
 0.747
ELOB
Elongin B.
     
 0.706
ACOT8
Acyl-CoA thioesterase 8.
      
 0.701
CAND2
Cullin associated and neddylation dissociated 2 (putative).
     
 0.687
ACSS3
Acyl-CoA synthetase short chain family member 3.
      
 0.685
CAND1
Cullin associated and neddylation dissociated 1.
     
 0.677
CTNNB1
Beta catenin 1.
   
 
 0.663
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]