Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1245 aa)    
Predicted Functional Partners:
VIT
Vitrin.
    
 0.815
ZKSCAN2
Zinc finger with KRAB and SCAN domains 2.
      
 0.690
SEBOX
SEBOX homeobox.
   
  
 0.646
GPR84
G protein-coupled receptor 84.
      
 0.586
HIVEP3
Human immunodeficiency virus type I enhancer binding protein 3.
      
 0.585
SALL4
Spalt like transcription factor 4.
   
  
 0.567
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
  
 
0.561
IRX1
Iroquois homeobox 1.
   
  
 0.552
TET2
Tet methylcytosine dioxygenase 2.
      
 0.543
ARID4B
AT-rich interaction domain 4B.
    
 
 0.543
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.