Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)    
Predicted Functional Partners:
TMLHE
Trimethyllysine hydroxylase, epsilon.
      
 0.757
SLC25A43
Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.730
SLC25A30
Solute carrier family 25 member 30; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.715
P2RY8
P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family.
      
 0.686
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
      
 0.653
ALG8
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.651
CBL
Cbl proto-oncogene.
    
 0.627
CBLB
Cbl proto-oncogene B.
    
 0.627
ZNF536
Zinc finger protein 536.
   
  
 0.582
IL9R
Interleukin 9 receptor.
      
 0.573
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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