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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP4R3CProtein phosphatase 4 regulatory subunit 3C. (776 aa)    
Predicted Functional Partners:
PPP4C
Serine/threonine-protein phosphatase.
   
 0.979
PPP4R3A
Protein phosphatase 4 regulatory subunit 3A.
  
0.952
PPP4R2
Protein phosphatase 4 regulatory subunit 2.
   
 0.926
CRTC2
CREB regulated transcription coactivator 2.
     
 0.901
PPP4R3B
Protein phosphatase 4 regulatory subunit 3B.
  
  
 
0.901
PTPA
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    
 0.821
PPP3CB
Serine/threonine-protein phosphatase.
   
 0.715
PPP3CC
Serine/threonine-protein phosphatase.
   
 0.715
PPP3CA
Serine/threonine-protein phosphatase.
   
 0.715
PPP4R1
Protein phosphatase 4 regulatory subunit 1.
   
 
 0.654
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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