STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXO1Forkhead box O1. (651 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.993
SGK1
Non-specific serine/threonine protein kinase.
    
 0.967
CREBBP
CREB binding protein.
   
 0.964
SMAD2
Mothers against decapentaplegic homolog.
    
 0.959
SMAD3
Mothers against decapentaplegic homolog.
   
 0.957
STAT3
Signal transducer and activator of transcription.
   
 0.953
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.952
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.952
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.946
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 0.942
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.