STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXO1Forkhead box O1. (651 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.996
AKT2
Non-specific serine/threonine protein kinase.
    
 0.983
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.982
SMAD3
Mothers against decapentaplegic homolog.
   
 0.982
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.981
SMAD2
Mothers against decapentaplegic homolog.
    
 0.980
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.978
CREBBP
CREB binding protein.
   
 0.970
STAT3
Signal transducer and activator of transcription.
   
 0.961
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 0.955
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.