Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
KRT18-2IF rod domain-containing protein; Belongs to the intermediate filament family. (438 aa)    
Predicted Functional Partners:
KRT7
Keratin 7; Belongs to the intermediate filament family.
   
0.884
KRT19
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 0.840
ENSECAP00000033574
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 0.840
DES
Desmin; Belongs to the intermediate filament family.
    
 0.613
AK9
Uncharacterized protein.
    
 0.589
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.576
EPCAM
Epithelial cell adhesion molecule.
      
 0.524
KRT6B
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
0.513
KRT15
Keratin 13; Belongs to the intermediate filament family.
   
  0.507
KRT78
Keratin 78; Belongs to the intermediate filament family.
   
 0.492
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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