Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB6Zinc finger and BTB domain containing 6. (461 aa)    
Predicted Functional Partners:
KCTD2
Potassium channel tetramerization domain containing 2.
    
 0.734
BTBD7
BTB domain containing 7.
      
 0.698
KLHL18
Kelch like family member 18.
    
 0.692
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
 0.619
RASGRP1
RAS guanyl releasing protein 1.
   
 
 0.533
PAX4
Paired box 4.
    
 0.525
SOX8
SRY-box 8.
    
 0.500
DHRS11
Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.473
SPOPL
Speckle type BTB/POZ protein like.
   
 0.451
INKA1
Inka box actin regulator 1.
      
 0.430
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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