Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D17TBC1 domain family member 17. (650 aa)    
Predicted Functional Partners:
TBC1D15
TBC1 domain family member 15.
    
 0.979
FIS1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
    
 0.933
RAB7A
RAB7A, member RAS oncogene family.
    
 0.922
CCDC121
DUF4515 domain-containing protein.
    
   0.918
RAB7B
RAB7B, member RAS oncogene family.
   
 0.912
CLDN15
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
    
 0.852
TBC1D14
TBC1 domain family member 14.
      
 0.708
AKT1S1
AKT1 substrate 1.
   
  
 0.671
TBC1D19
TBC1 domain family member 19.
      
 0.636
PCMTD2
Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2.
      
 0.609
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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