Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)    
Predicted Functional Partners:
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
IRAK1
Interleukin 1 receptor associated kinase 1.
   
 0.999
TIRAP
TIR domain containing adaptor protein.
   
0.997
IRAK2
Interleukin 1 receptor associated kinase 2.
   
 0.996
TLR6
Toll-like receptor.
   
 0.995
TLR1
Toll-like receptor.
   
 0.995
TLR5
Toll like receptor 5; Belongs to the Toll-like receptor family.
    
 0.994
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.994
TLR7
Toll like receptor 7; Belongs to the Toll-like receptor family.
   
 0.988
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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