Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD34AAnkyrin repeat domain 34A. (496 aa)    
Predicted Functional Partners:
FAM151B
Family with sequence similarity 151 member B.
      
 0.662
SYNGR3
Synaptogyrin.
   
  
 0.562
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
 
 0.549
FAM110B
Family with sequence similarity 110 member B.
      
 0.546
POLR2H
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
   
 
 0.489
POLR3C
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.471
ZFYVE9
Zinc finger FYVE domain-containing protein.
      
 0.468
ZFYVE16
Zinc finger FYVE-type containing 16.
      
 0.468
GTF2E1
General transcription factor IIE subunit 1.
      
 0.448
NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2.
   
 0.423
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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