Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POU3F4POU domain protein. (361 aa)    
Predicted Functional Partners:
PNMA5
PNMA family member 5.
   
  
 0.775
LONRF3
LON peptidase N-terminal domain and ring finger 3.
      
 0.631
SOX3
SRY-box transcription factor 3.
   
 0.582
SOX2
SRY-box transcription factor 2.
   
 0.574
PAX6
Paired box 6.
   
 0.545
SOX10
SRY-box transcription factor 10.
   
 0.507
CRX
Cone-rod homeobox.
   
 0.494
C7H11orf53
Chromosome 7 C11orf53 homolog.
    
 
 0.491
ZNF521
Zinc finger protein 521.
    
 0.487
LMX1A
LIM homeobox transcription factor 1 alpha.
   
 0.474
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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