Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBR1T-box brain transcription factor 1. (682 aa)    
Predicted Functional Partners:
SATB2
DNA-binding protein SATB.
   
 
 0.959
CUX1
Homeobox protein cut-like.
    
 
 0.941
PAX6
Paired box 6.
   
 0.922
FOXG1
Forkhead box G1.
   
 
 0.893
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 
 0.877
EMX1
Empty spiracles homeobox 1.
    
 0.877
RELN
Reelin.
    
 
 0.875
FEZF2
FEZ family zinc finger 2.
   
 
 0.872
NES
Nestin; Belongs to the intermediate filament family.
    
 
 0.863
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.802
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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