Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KCTD3Potassium channel tetramerization domain containing 3. (816 aa)    
Predicted Functional Partners:
SHKBP1
SH3KBP1 binding protein 1.
    
  0.924
FBXW8
F-box and WD repeat domain containing 8.
     
 0.884
LRRC40
Leucine rich repeat containing 40.
    
  0.817
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.815
LDB2
LIM domain binding 2.
      
 0.805
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
    
   0.783
NUDCD1
NudC domain containing 1.
    
   0.783
KCTD7
Potassium channel tetramerization domain containing 7.
    
 
 0.692
GPATCH2
G-patch domain containing 2.
      
 0.682
SPATA17
Spermatogenesis associated 17.
      
 0.632
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (20%) [HD]