Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THUMPD3THUMP domain containing 3. (506 aa)    
Predicted Functional Partners:
F6TUL1_HORSE
Uncharacterized protein.
    
 0.879
SETD5
SET domain containing 5.
      
 0.854
TRMT112
tRNA methyltransferase subunit 11-2.
    
 
 0.819
MICU3
Mitochondrial calcium uptake family member 3.
    
   0.789
ITSN2
Intersectin 2.
   
 0.674
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3.
      
 0.630
TRMT11
tRNA methyltransferase 11 homolog.
   
 
 0.594
INTS10
Integrator complex subunit 10.
      
 0.577
UTP20
UTP20 small subunit processome component.
      
 0.572
EIF4ENIF1
Eukaryotic translation initiation factor 4E nuclear import factor 1.
    
 
 0.527
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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