Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100071666RanBP2-type domain-containing protein. (413 aa)    
Predicted Functional Partners:
RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1.
   
0.997
F7CNV6_HORSE
Uncharacterized protein.
   
 0.982
OTULIN
OTU deubiquitinase with linear linkage specificity.
    
 0.944
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.891
BIRC2
Baculoviral IAP repeat containing 3.
   
 0.890
TNF
Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]
    
 0.882
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.880
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.866
XIAP
X-linked inhibitor of apoptosis.
   
 0.836
NOD2
Nucleotide binding oligomerization domain containing 2.
   
 
 0.828
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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