Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (662 aa)    
Predicted Functional Partners:
SLC2A5
Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
   
  
 0.883
LCT
Lactase.
   
  
 0.669
SLC43A2
Solute carrier family 43 member 2.
      
 0.630
TAS1R3
Taste 1 receptor member 3.
      
 0.592
SLC26A3
Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
  
 0.586
SLC1A1
Amino acid transporter.
   
  
 0.568
PNLIP
Pancreatic triacylglycerol lipase.
      
 0.523
SLC2A2
Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.518
TMPRSS15
Transmembrane serine protease 15; Belongs to the peptidase S1 family.
   
  
 0.501
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.493
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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