Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KRT84Keratin 84; Belongs to the intermediate filament family. (575 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.891
DSG2
Desmoglein 2.
   
 0.833
DSG1
Desmoglein 1.
   
 0.828
KRTAP24-1
Keratin associated protein 24-1.
      
 0.793
KRTAP27-1
Keratin associated protein 27-1.
     
 0.782
CAPN12
Calpain 12; Belongs to the peptidase C2 family.
   
 0.717
KRTAP15-1
Keratin associated protein 15-1.
   
  
 0.643
KRTAP11-1
Keratin associated protein 11-1.
   
  
 0.607
LOC111770797
Uncharacterized protein.
   
  
 0.605
KRT7
Keratin 7; Belongs to the intermediate filament family.
   
  0.603
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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