Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO4R-spondin 4. (238 aa)    
Predicted Functional Partners:
ZNRF3
Zinc and ring finger 3.
    
 0.938
RNF43
Ring finger protein 43.
    
 0.934
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
    
 0.924
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.892
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.884
RSPO1
R-spondin 1.
     
  0.803
RSPO3
R-spondin 3.
  
  
0.800
RSPO2
R-spondin 2.
     
  0.743
NOL4L
Nucleolar protein 4 like.
   
  
 0.632
POGLUT1
Protein O-glucosyltransferase 1.
      
 0.579
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.