STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OR51A7Olfactory receptor. (312 aa)    
Predicted Functional Partners:
GNG13
G protein subunit gamma 13.
    
  0.753
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
  0.750
GNAL
G protein subunit alpha L.
    
 0.678
GNG7
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.623
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
  0.617
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
  0.606
GRK3
G protein-coupled receptor kinase 3.
    
  0.558
GRK3-2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
  0.558
OAZ2
Uncharacterized protein.
      
 0.516
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]
      
 0.446
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (20%) [HD]