STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H9GZQ2_HORSEIg-like domain-containing protein. (170 aa)    
Predicted Functional Partners:
PIGR
Polymeric immunoglobulin receptor.
   
 0.570
C1QC
Complement C1q C chain.
   
 0.568
SYK
Tyrosine-protein kinase.
    
 0.545
FCER1A
High affinity immunoglobulin E receptor alpha subunit.
    
  0.544
C1QB
Complement C1q B chain.
     
 0.544
MS4A2
Membrane spanning 4-domains A2.
     
 0.542
PLG
Plasmin heavy chain A; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be m [...]
   
 
  0.538
LOC100051526
Uncharacterized protein.
    
  0.533
JCHAIN
Joining chain of multimeric IgA and IgM.
   
 
 0.533
LYN
Tyrosine-protein kinase.
    
  0.533
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.