STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACE2Angiotensin-converting enzyme. (805 aa)    
Predicted Functional Partners:
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
     
 0.994
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
    
 
 0.984
MME
Membrane metalloendopeptidase.
   
 
 0.977
REN
Renin; Belongs to the peptidase A1 family.
   
  
 0.963
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.954
PRCP
Prolylcarboxypeptidase.
     
 0.950
LOC111767504
Aminopeptidase.
   
  
 0.943
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
      
 0.938
MEP1A
Meprin A subunit.
   
 
 0.938
MEP1B
Meprin A subunit.
   
 
 0.918
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.